Looks good, everything I liked about the first movie's tone is back. Probably the movie I'm looking forward to most this year after Endgame.
Mysterio actually looks badass, that's pretty much a feat in itself.
I always cringe when I see someone get tranqued in movies, I worry that one day, somebody's going to fall on the dart and get it driven into their neck
I have one tiny quibble, and this is a little more about how Spider-Man is handled across media in general: I don't like how he's becoming a hero who's about the suit, and getting upgrades to win the day. I'll reserve judgment for how the stealth suit is used in this film, but I've been seeing the trend in the comics and video games, and it feels wrong. (And yes, I get the need to sell toys, and I'm already planning to snap up the Marvel Legends for this film.)
That all said, I think the red-and-black suit looks sharp. Arguably the "original" colors for Spider-Man, I wouldn't mind if this became the default MCU suit.