This comes off of what I was saying in another thread about how perhaps it's time for Marvel to do a neo-Silver Age and take things back to basics in a way.
It's just something I mulled over while at work, so it's far from complete.
But here goes.
Basically, the idea for this neo-Silver Age will be the "back to basics" approach. The idea will be to have the stories gradually build up on each other, such that each issue does contribute to something down the road, but if you miss one or two you won't have a hard time catching up. Main flagship characters like Spider-Man and The Avengers will be written with an eye to an "all-ages" audience, while select characters like Deadpool and Wolverine will be done by hand-picked teams selected for their ability to do "mature" without grimdark or 90s!extreme. Politics and social issues will be handled with wisdom, meaning sparingly and in measured doses; for example, a single well-written Luke Cage issue dealing with racism would have more of an impact than a series of slapdash issues.
1. Avengers (AKA "Avengers Blue"): In this take on things, the Avengers are a secondary arm of SHIELD; they have their autonomy and can act on threats as they feel necessary, but they ultimately report to SHIELD and SHIELD has the right to send them into the field as needs be. Captain America serves as the team leader, and regular members include War Machine, Falcon, Quicksilver, Scarlet Witch, Black Widow, Hulk (for rehabilitation), Winter Soldier (ditto), Giant Man / Hank Pym, Wasp / Janet Van Dyne, Hawkeye, Tygra, and Ms. Marvel / Carol Danvers.
2. "Avengers Red": SHIELD considers them an Avengers reserve element, but for the most part it's Iron Man and a loose coalition of "we help the helpless" heroes & up-and-comers he's trying to tutor. Aside from Iron Man, we have The Defenders, Ant Man / Scott, Yellowjacket, Spider-Man / Peter Parker, Iron Spider, She-Hulk, Iron Heart, Rescue, Squirrel Girl, and Ms. Marvel / (can't remember the current woman's name). Spidey, Iron-Man, and The Defenders would have their own titles, while the rest are together under the main "Avengers Red" title. (Miles Morales would be Spidey's bestie and one of the few people to know his secret; he helps Peter maintain his gear and later comes to be Oracle to Peter's Batman.)
3. X-Teams: Rather than keep all of the X-Men in a single location, Professor X has trusted several key leaders - such as Cyclops, Storm, and Colossus - to take charge of different groups of mutants, each team operating out of some sort of private school; X and Beast have the Xavier Institute, Cyclops has a facility near Chicago, Storm has a facility in California, and Colossus is up in Colorado. Each team has its own title.
4. Loose Cannons: These are individuals like Thor, Wolverine, Black Panther, The Punisher, Deadpool, and Dr. Strange who can be game-changers when encouraged (or coerced) into fighting alongside one faction or another, but they have their reasons for being lone wolves. IE, Thor is splitting his time between realms, Wolverine is constantly being bugged by both Alpha Flight and the X-Men, Deadpool is Deadpool, et cetra. Most of these characters would have their own titles, with many of those titles being aimed at "mature" audiences.
5. Guardians: Star-Lord's team will be the Guardians of the Galaxy, while Star Hawk leads the Galactic Guardians. Yandu is with the latter; in this incarnation, he's a Captain Harlock type who leads a crew of penitent space pirates, keeping him a little more in line with the movies.
6. Et cetra: Of course, we'd have Alpha Flight, Excalibur (under Captain Britain), The Fantastic Four, and a few other groups in the background, with whatever characters I couldn't bring to mind filtering in and out as well. A few will have their own titles, while others will be supporting characters for others.